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Anti -IL-17A Receptor Rabbit pAb

價格: 在線咨詢
貨號:
DRF101693
產品規格:
100 μL
Applications:
Species:
購買數量:
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Product Information


Description

IL-17A Receptor rabbit polyclonal

Protein full name

Interleukin-17 receptor A

Synonyms

IL17RA, CANDF5, CD217, CDw217, IL-17RA, IL17R, hIL-17R, interleukin 17 receptor A, IMD51, IL-17A Receptor

Immunogen

KLH conjugated Synthetic peptide

corresponding to Human IL-17A Receptor

Isotype

IgG

Purity

Affinity purification

Predicted MW.

96 kDa

Observed MW.

110 kDa

Uniprot ID

Q96F46




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human

1: 500-1: 1000

Jurkat, HTP-1, A20




Background


Interleukin 17 receptor A, also known as IL17RA and CDw217 (cluster of differentiation w217) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure.

     



Images



wb-10.jpg

Western blot analysis of IL-17A Receptor (GB11586) at dilution of 1: 600

Lane 1: Jurkat cell lysate

Lane 2: HTP-1 cell lysate

Lane 3: A20 cell lysate





Storage



Storage

Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles

Storage Buffer

PBS with 0.02%sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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