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產品詳情
操作說明
注意事項
Product Information
|
Description |
Pannexin 1 rabbit polyclonal antibody |
|
Protein full name |
Pannexin-1 |
|
Synonyms |
Panx1, innexin, MRS1, PX1 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Pannexin 1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
48 kDa |
|
Observed MW. |
48 kDa |
|
Uniprot ID |
Q9JIP4, P60570 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
testis |
Background
PANX1, also named as MRS1, belongs to the pannexin family. It plays a role as a Ca2+-leak channel to regulate ER Ca2+ homeostasis. It is a structural component of the gap junctions and the hemichannels. PANX1 induced the formation of intercellular channels with characteristics of gap junctions. The PANX1 and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.
Images
|
|
Western blot analysis of PANX1 (GB111044) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區黃山路602號合肥國家大學科技園A401室