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Anti -Cyclin D1 Rabbit pAb

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貨號:
KT011855
產品規格:
Applications:
Species:
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Product Information


Description

Cyclin D1 rabbit polyclonal antibody

Protein full name

G1/S-specific cyclin-D1

Synonyms

Ccnd1, Cyl-1, B-cell lymphoma 1 protein, BCL-1, Parathyroid adenomatosis 1, PRAD1, BCL1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Cyclin D1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

33 kDa

Observed MW.

33 kDa

Uniprot ID

P24385, P25322, P39948




Applications


Applications

Species

Dilution

Positive Sample

WB

Human, Mouse, Rat

1: 500-1: 1000

MCF-7, A431, SH-SY5Y, THP-1, L929, RAW 264.7, C6, PC-12




Background


The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb.




Images


Picture 1.png

Western blot analysis of cyclinD1 (GB111935) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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