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產品詳情
操作說明
注意事項
Product Information
|
Description |
ADAR1 rabbit polyclonal antibody |
|
Protein full name |
Double-stranded RNA-specific adenosine deaminase |
|
Synonyms |
DRADA, RNA adenosine deaminase 1, Adar, Adar1, 136kDa double stranded RNA binding protein, AGS6, Adenosine deaminase acting on RNA 1 A, Interferon inducible protein 4, RNA adenosine deaminase 1 |
|
Immunogen |
Recombinant protein corresponding to Mouse ADAR1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
130 kDa |
|
Observed MW. |
110 kDa |
|
Uniprot ID |
P55265 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human |
1: 500-1: 1000 |
293T, Jurkat, HepG2, HeLa, DU145 |
Background
ADAR1 is also named as ADAR1, DSRAD, G1P1, IFI4. It convert selected adenosine residues into inosine in substrate RNAs containing a relatively short dsRNA region. The human ADAR1 gene specifies two size forms of RNA-specific adenosine deaminase, an interferon (IFN) inducible ～150 kDa protein and a constitutively expressed N-terminally truncated ～110 kDa protein, encoded by transcripts with alternative exon 1 structures that initiate from different promoters. It has 5 isoforms produced by alternative promoter usage and alternative splicing. Defects in ADAR are a cause of dyschromatosis symmetrical hereditaria (DSH).ADAR1 can form respective homodimers, and this association is essential for its enzymatic activities.
Images
|
|
Western blot analysis of ADAR1 (GB111458) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區黃山路602號合肥國家大學科技園A401室