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產品詳情
操作說明
注意事項
Product Information
|
Description |
Cyclophilin A rabbit polyclonal antibody |
|
Protein full name |
Peptidyl-prolyl cis-trans isomerase A |
|
Synonyms |
PPIase A, Cyclophilin A, Ppia, Cyclosporin A-binding protein, Rotamase A, SP18 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Cyclophilin A |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
18 kDa |
|
Observed MW. |
18 kDa |
|
Uniprot ID |
P62937, P17742, P10111 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
heart, brain, thymus |
Background
Cyclophilin A, also named as PPIA and Rotamase A, belongs to the cyclophilin-type PPIase family and PPIase A subfamily. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIA forms a trimolecular complex with cyclophilin and calcineurins to inhibit calcineurin phosphatase activity. PPIA is incorporated into the virion of the type 1 human immunodeficiency virus (HIV-1) via a direct interaction with the capsid domain of the viral Gag polyprotein and is crucial for efficient viral replication.
Images
|
|
Western blot analysis of cyclophilin-A (GB111283) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區黃山路602號合肥國家大學科技園A401室