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產品詳情
操作說明
注意事項
Product Information
|
Description |
CD3 rabbit monoclonal |
|
Protein full name |
T-cell surface glycoprotein CD3 epsilon chain |
|
Synonyms |
CD3E, IMD18, T3E, TCRE, CD3e molecule |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to human CD3 epsilon |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
|
|
Uniprot ID |
P07766 |
Applications
|
applications |
species |
dilution |
Positive tissue |
|
IHC |
Human, Mouse, Rat |
1: 50-1: 200 |
spleen, liver |
|
IF |
Human, Mouse, Rat |
1: 50-1: 200 |
spleen, liver |
Background
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
Images
|
Immunohistochemistry analysis of paraffin-embedded human spleen using CD3(GB13014) at dilution of 1:100.
|
|
Immunohistochemistry analysis of paraffin-embedded mouse liver using CD3(GB13014) at dilution of 1:100.
|
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區黃山路602號合肥國家大學科技園A401室