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Anti -Glutamine Synthetase Rabbit pAb

價格：在線咨詢

貨號：

KT011497

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

H,M,R

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	Glutamine Synthetase rabbit polyclonal antibody
Protein full name	Glutamine synthetase
Synonyms	Cell proliferation-inducing protein 59, GLNA, GLNS, GLUL,Glutamate ammonia ligase, Glutamate decarboxylase, Glutamine synthetase, GS, PIG43, PIG59,Proliferation inducing protein 43
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse Glutamine Synthetase
Isotype	IgG
Purity	Affinity purification
Predicted MW.	42 kDa
Observed MW.	42 kDa
Uniprot ID	P15104, P15105, P09606

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1: 500-1: 1500	liver, lung, kidney

Background

Glutamine Synthetase catalyzes the conversion of ammonia and glutamate to glutamine. The function of Glutamine Synthetase is the detoxification of brain ammonia. It also has an important role in the metabolic regulation of neurotransmitter glutamate. Because of the multiple functions and importance of Glutamine Synthetase in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of Glutamine Synthetase is controlled by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer's disease, particularly in the vicinity of senile plaques. It is also decreased under conditions of glucose deprivation. The level of expression of Glutamine Synthetase is increased during ischemia in vivo or hypoxia in culture.

Images

Picture 1.png

Western blot analysis of Glutamune synthetase (GB11736) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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