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Anti - E Cadherin Rabbit pAb

價格: 在線咨詢
貨號:
KT011871
產品規(guī)格:
100 μL
Applications:
WB/IHC/IF
Species:
HMR/HMR
購買數量:
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Product Information



Description

E Cadherin rabbit polyclonal antibody

Protein full name

Cadherin-1

Synonyms

CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO, cadherin 1, Epithelial Cadherin, E-Cadherin, CAM 120/80

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse E Cadherin

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membrane, Cytoplasm

Predicted MW.

98 kDa

Observed MW.

135 kDa

Uniprot ID

P12830, P09803, Q9R0T4





Applications



Applications

Species

Dilution

Positive Sample

WB

Human, Mouse, Rat

1: 1000-1: 2000

spleen, lung, kidney

IHC/IF

Human, Mouse, Rat

1: 200-1: 1500

colon, liver, prostate, stomach, uterus




Background


Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.




Images


Western blot analysis of E-cadherin (GB11082) at dilution of 1: 1000

Western blot analysis of E-cadherin (GB11082) at dilution of 1: 1000


Immunohistochemistry of paraffin embedded human liver using E-cadherin (GB11082) at dilution of 1: 1000 (400x lens)


Immunohistochemistry of paraffin embedded human liver using E-cadherin (GB11082) at dilution of 1: 500 (350x lens)


Immunohistochemistry of paraffin embedded human prostate using E-cadherin (GB11082) at dilution of 1: 500 (400x lens)

Immunohistochemistry of paraffin embedded mouse liver using E-cadherin (GB11082) at dilution of 1: 500 (400x lens)

Immunohistochemistry of paraffin embedded mouse stomach using E-cadherin (GB11082) at dilution of 1: 500 (300x lens)


Immunohistochemistry of paraffin embedded rat colon using E-cadherin (GB11082) at dilution of 1: 500 (300x lens)

Immunofluorescence of paraffin embedded mouse colon using E-cadherin (GB11082) at dilution of 1: 1900 (400x lens)

Immunofluorescence of paraffin embedded mouse uterus using E-cadherin (GB11082) at dilution of 1: 1900 (400x lens)


Immunofluorescence of paraffin embedded rat stomach using E-cadherin (GB11082) at dilution of 1: 1900 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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