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Anti -Asialoglycoprotein Receptor 1/HL-1 Rabbit pAb

價格: 在線咨詢
貨號:
KT011927
產品規格:
100 μL
Applications:
WB
Species:
MR
購買數量:
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產品詳情 操作說明 注意事項

Product Information


Description

ASGR1 rabbit polyclonal antibody

Protein full name

Asialoglycoprotein receptor 1

Synonyms

ASGP-R 1, Hepatic lectin 1, HL-1, mHL-1, Asgr1, Asgr

Immunogen

Recombinant protein corresponding to Mouse ASGR1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

33 kDa

Observed MW.

42 kDa

Uniprot ID

P34927, P02706




Applications


Applications

Species

Dilution

Positive Sample

WB

Mouse, Rat

1: 500-1: 1000

liver




Background


Asialoglycoprotein receptor (ASGPR), also known as the hepatic galactose/N-acetylglucosamine (GlcNAc) receptor or Ashwell receptor, is a C-type lectin expressed exclusively in hepatic parenchymal cells. ASGPR consists of two subunits, a major subunit (ASGR1, HL-1) and a minor subunit (ASGR2, HL-2), and specifically recognizes terminal β-linked galactose or GlcNAc on circulating glycoproteins or cells. This receptor plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins that contain terminal galactose or GlcNAc residues. ASGPR may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery.




Images


Picture 1.png

Western blot analysis of ASGR1 (GB111336) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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