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Product Information
Description |
COX2 rabbit polyclonal antibody |
Protein full name |
Prostaglandin G/H synthase 2 |
Synonyms |
PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2, prostaglandin-endoperoxide synthase 2 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse COX2 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Microsome membrane |
Uniprot ID |
Q05769, P35355 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
IHC/IF |
Human, Mouse |
1: 500-1: 2000 |
cerebral infarction, colon cancer, stomach |
Background
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.
Images
|
Immunohistochemistry of paraffin embedded human colon cancer using COX2 (GB11077-1) at dilution of 1:500 (400x lens) |
|
Immunohistochemistry of paraffin embedded mouse stomach using COX2 (GB11077-1) at dilution of 1:500 (300x lens) |
|
Immunofluorescence of paraffin embedded human colon cancer using COX2 (GB11077-1) at dilution of 1:1000 (300x lens) |
|
Immunofluorescence of paraffin embedded mouse cerebral infarction using COX2 (GB11077-1) at dilution of 1:1000 (400x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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