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Anti -Inhibin alpha Rabbit pAb

價格: 在線咨詢
貨號:
KT012035
產品規格:
Applications:
IHC/IF
Species:
Rat
購買數量:
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Product Information


Description

Inhibin alpha rabbit polyclonal antibody

Protein full name

Inhibin alpha chain

Synonyms

Inha, A inhibin subunit precursor, IHA, INHA, Inhibin alpha chain precursor

Immunogen

Recombinant protein corresponding to Human Inhibin alpha

Isotype

IgG

Purity

Affinity purification

Subcellular location

Secreted

Uniprot ID

P17490




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Rat

1: 900-1: 1800

brain, lung, spleen




Background


The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.




Images


Immunohistochemistry of paraffin embedded rat brain using Inhibin-Alpha (GB111221) at dilution of 1:900 (400x lens)

Immunohistochemistry of paraffin embedded rat lung using Inhibin-Alpha (GB111221) at dilution of 1:900 (400x lens)

Immunohistochemistry of paraffin embedded rat spleen using Inhibin-Alpha (GB111221) at dilution of 1:900 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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