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Anti -Osteoprotegerin Rabbit pAb
價格：
在線咨詢
貨號：
KT012052
產品規格：
100 μL
Applications：
IHC/IF
Species：
M/R
購買數量：
產品詳情
操作說明
注意事項
Product Information
|
Description |
Osteoprotegerin rabbit polyclonal antibody |
|
Protein full name |
Tumor necrosis factor receptor superfamily member 11B |
|
Synonyms |
TNFRSF11B, OCIF, OPG, PDB5, TR1, tumor necrosis factor receptor superfamily member 11b, TNF receptor superfamily member 11b |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Osteoprotegerin |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Secreted |
|
Uniprot ID |
O08712, O08727 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
IHC/IF |
Mouse, Rat |
1: 100-1: 400 |
bone |
Background
Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.
Images
|
Immunohistochemistry of paraffin embedded mouse bone using OPG (GB11151) at dilution of 1:200 (100x lens) |
|
Immunohistochemistry of paraffin embedded rat bone using OPG (GB11151) at dilution of 1:200 (100x lens) |
|
|
Immunofluorescence of paraffin embedded mouse bone using OPG (GB11151) at dilution of 1:100 (100x lens)
|
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區黃山路602號合肥國家大學科技園A401室