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400-1016-218
聯系方式
- 手機：400-1016-218
- Q Q：355185756
- 郵箱：355185756@qq.com
- 地址：安徽省合肥市高新區黃山路602號合肥國家大學科技園A401室
產品詳情
操作說明
注意事項
Product Information
|
Description |
FUS rabbit polyclonal antibody |
|
Protein full name |
RNA-binding protein FUS |
|
Synonyms |
Protein pigpen, Fus, 75 kDa DNA pairing protein, ALS6, FUS CHOP, FUS1, POMp75, Fusion (involved in t(12;16) in malignant liposarcoma), hnRNP P2, Fusion gene in myxoid liposarcoma, Heterogeneous nuclear ribonucleoprotein P2, Oncogene TLS |
|
Immunogen |
Recombinant protein corresponding to Mouse FUS |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Nucleus |
|
Uniprot ID |
P56959 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
IHC/IF |
Mouse |
1: 800-1: 2000 |
brain, pancreas, Skeletal muscle |
Background
FUS (also named TLS and POMp75) belongs to the RRM TET family. FUS may play a role in the maintenance of genomic integrity; it binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. FUS is also an RNA-binding protein, and its links to neurodegenerative disease proffer the intriguing possibility that altered RNA metabolism or RNA processing may underlie or contribute to neuron degeneration. FUS may be a cause of angiomatoid fibrous histiocytoma (AFH) and is implicated in certain forms of amyotrophic lateral sclerosis (ALS) and frontotemporal dementias (FTDs) such as frontotemporal lobar dementia with ubiquitin inclusions (FTLD-U).
Images
|
|
Immunofluorescence of paraffin embedded mouse brain using FUS (GB111365) at dilution of 1:1000 (400x lens) |
|
|
Immunofluorescence of paraffin embedded mouse pancreas using FUS (GB111365) at dilution of 1:1000 (400x lens) |
|
|
Immunofluorescence of paraffin embedded mouse Skeletal muscle using FUS (GB111365) at dilution of 1:1000 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區黃山路602號合肥國家大學科技園A401室