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Anti -Dnmt3a Rabbit pAb

價格: 在線咨詢
貨號:
KT012151
產(chǎn)品規(guī)格:
100 μL
Applications:
IHC/IF
Species:
M,R
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information

Description

Dnmt3a rabbit polyclonal antibody

Protein full name

DNA (cytosine-5)-methyltransferase 3A

Synonyms

Dnmt3a, DNA methyltransferase MmuIIIA, DNA MTase MmuIIIA, M.MmuIIIA, Dnmt3a

Immunogen

Recombinant protein corresponding to Mouse Dnmt3a

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus, Cytoplasm

Uniprot ID

O88508, Q1LZ53





Applications

Applications

Species

Dilution

Positive Sample

IHC/IF

Mouse, Rat

1: 500-1: 3200

colon, embryonic mouse, embryonic rat, kidney, lymph node, placenta, spleen, testis





Background

Inactivation of tumor suppressor genes is a key component of the development of all common forms of human cancers. Aberrant methylation may contribute to many of the changes, both physiological and pathological, associated with aging, including tumor development. Hypermethylation of CpG island-containing promoters is associated with the inactivation of genes important to tumor angiogenesis and progression. DNA methytransferase (DNMT3a) is necessary for the maintenance of the methylation process.





Images

Immunohistochemistry of paraffin embedded mouse embryonic mouse using Dnmt3a (GB111355) at dilution of 1:3200 (400x lens)

Immunohistochemistry of paraffin embedded mouse placenta using Dnmt3a (GB111355) at dilution of 1:3200 (400x lens)

Immunohistochemistry of paraffin embedded mouse spleen using Dnmt3a (GB111355) at dilution of 1:3200 (400x lens)

Immunohistochemistry of paraffin embedded mouse testis using Dnmt3a (GB111355) at dilution of 1:3200 (400x lens)

Immunohistochemistry of paraffin embedded rat colon using Dnmt3a (GB111355) at dilution of 1:3200 (400x lens)
Immunohistochemistry of paraffin embedded rat placenta using Dnmt3a (GB111355) at dilution of 1:3200 (400x lens)

Immunohistochemistry of paraffin embedded rat spleen using Dnmt3a (GB111355) at dilution of 1:3200 (400x lens)

Immunofluorescence of paraffin embedded mouse kidney using Dnmt3a (GB111355) at dilution of 1:1600 (400x lens)

Immunofluorescence of paraffin embedded mouse placenta using Dnmt3a (GB111355) at dilution of 1:1600 (400x lens)

Immunofluorescence of paraffin embedded mouse testis using Dnmt3a (GB111355) at dilution of 1:1600 (400x lens)

Immunofluorescence of paraffin embedded rat embryonic rat using Dnmt3a (GB111355) at dilution of 1:1600 (400x lens)

Immunofluorescence of paraffin embedded rat lymph node using Dnmt3a (GB111355) at dilution of 1:1600 (400x lens)





Storage

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).



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