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Anti -KMT3C/SMYD2 Rabbit pAb

價(jià)格: 在線咨詢(xún)
貨號(hào):
KT012155
產(chǎn)品規(guī)格:
Applications:
IHC/IF
Species:
M,R
購(gòu)買(mǎi)數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

KMT3C/SMYD2 rabbit polyclonal antibody

Protein full name

N-lysine methyltransferase SMYD2

Synonyms

Histone methyltransferase SMYD2, SET and MYND domain-containing protein 2, Smyd2, Lysine N-methyltransferase 3C, MGC119305, N lysine methyltransferase SMYD2

Immunogen

Recombinant protein corresponding to Mouse SMYD2

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus, Cytoplasm

Uniprot ID

Q8R5A0, Q7M6Z3




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Mouse, Rat

1: 1000-1: 4000

Bone fibroids, brain, heart, Skeletal muscle




Background


Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Has also methyltransferase activity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53.




Images


Immunohistochemistry of paraffin embedded mouse heart using SMYD2 (GB111583) at dilution of 1:2000 (400x lens)

Immunofluorescence of paraffin embedded mouse brain using SMYD2 (GB111583) at dilution of 1:2000 (400x lens)

Immunofluorescence of paraffin embedded mouse Skeletal muscle using SMYD2 (GB111583) at dilution of 1:1000 (400x lens)

Immunofluorescence of paraffin embedded rat Bone fibroids using SMYD2 (GB111583) at dilution of 1:2000 (400x lens)

Immunofluorescence of paraffin embedded rat heart using SMYD2 (GB111583) at dilution of 1:2000 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.
Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.
Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).



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