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產品詳情
操作說明
注意事項
Product Information
|
Description |
WDFY3 rabbit polyclonal antibody |
|
Protein full name |
WD repeat and FYVE domain-containing protein 3 |
|
Synonyms |
ALFY, Autophagy linked FYVE protein, KIAA0993, WDFY3, ZFYVE25, BWF1 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse WDFY3 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cytoplasm, Membrane, Nucleus |
|
Uniprot ID |
Q8IZQ1 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
IHC/IF |
Human |
1: 400-1: 1300 |
colon, colon cancer |
Background
WDFY3 also called ALFY, is a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy.This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy.
Images
|
Immunohistochemistry of paraffin embedded human colon using WDFY3 (GB111969) at dilution of 1:700 (400x lens) |
|
|
Immunohistochemistry of paraffin embedded human colon cancer using WDFY3 (GB111969) at dilution of 1:700 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區黃山路602號合肥國家大學科技園A401室