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Anti -ADRM1/ARM-1 Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT012243
產(chǎn)品規(guī)格:
100 μL
Applications:
IHC/IF
Species:
HMR
購(gòu)買(mǎi)數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

ADRM1 rabbit polyclonal antibody

Protein full name

Proteasomal ubiquitin receptor ADRM1

Synonyms

110 kDa cell membrane glycoprotein, Gp110, Adhesion-regulating molecule 1, ARM-1, Rpn13 homolog, ADRM1, Gp110

Immunogen

Recombinant protein corresponding to Mouse ADRM1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus

Uniprot ID

Q16186, Q9JMB5




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Human, Mouse, Rat

1: 1000-1: 2000

brain, breast cancer, colon cancer, esophagus, lung




Background


ADRM1 is a 407 amino acid protein that localizes to both the nucleus and the cytoplasm and is thought to be involved in protein recruitment and cell adhesion. An integral membrane protein, ADRM1 functions to recruit UCH-L5, a deubiquitinating enzyme, to the 26S proteasome, and once at the proteasome it promotes the activity of UCH-L5. Additionally, ADRM1 is thought to mediate lymphocyte adhesion in endothelial cells and may thus play a role in lymphocyte homing. ADRM1 expression is induced by IFN-g in some cancer cell lines and its expression is upregulated in other metastatic cells, suggesting a role in carcinogenesis.




Images


Immunohistochemistry of paraffin embedded human breast cancer using ADRM1 (GB111263) at dilution of 1:1000 (400x lens)

Immunohistochemistry of paraffin embedded human colon cancer using ADRM1 (GB111263) at dilution of 1:1000 (400x lens)

Immunohistochemistry of paraffin embedded human esophagus using ADRM1 (GB111263) at dilution of 1:1000 (400x lens)

Immunohistochemistry of paraffin embedded mouse brain using ADRM1 (GB111263) at dilution of 1:1000 (400x lens)

Immunohistochemistry of paraffin embedded mouse lung using ADRM1 (GB111263) at dilution of 1:1000 (400x lens)

Immunohistochemistry of paraffin embedded rat brain using ADRM1 (GB111263) at dilution of 1:1000 (400x lens)

Immunohistochemistry of paraffin embedded rat lung using ADRM1 (GB111263) at dilution of 1:1000 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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