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Anti -CD68 Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
DRF10184
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購(gòu)買(mǎi)數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

CD68 rabbit polyclonal

Protein full name

Macrosialin

Synonyms

CD68,CD68 Molecule,Scavenger Receptor

Class D, Member 1 ,Macrophage Antigen

 CD68,GP110 ,Macrosialin,SCARD1,

LAMP4 

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse CD68 

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membrane,Endosome membrane,

Lysosome membrane

Uniprot ID

P31996



Applications


applications

species

dilution

Positive tissue

IHC

Mouse, Rat

1: 300-1: 1000

hepatitis, spleen, lung, liver

IF

Mouse, Rat

1: 500-1: 1000

spleen



Background



Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.




Images



Immunohistochemistry analysis of paraffin-embedded mouse hepatitis using CD68 (GB11067) at dilution of 1: 500

Immunohistochemistry analysis of paraffin-embedded mouse spleen using CD68 (GB11067) at dilution of 1: 500


Immunohistochemistry analysis of paraffin-embedded mouse lung using CD68 (GB11067) at dilution of 1: 500

Immunohistochemistry analysis of paraffin-embedded mouse liver using CD68 (GB11067) at dilution of 1: 500

Immunofluorescent analysis of paraformaldehyde-fixed rat spleen using 

CD68 (GB11067) at dilution of 1: 500

Immunofluorescent analysis of paraformaldehyde-fixed mouse bone using CD68(GB11067) at dilution of 1:1000

Immunohistochemistry analysis of paraffin-embedded rat lymph node using CD68(GB11067) at dilution of 1:1000


Immunohistochemistry analysis of paraffin-embedded rat spleen using CD68(GB11067) at dilution of 1:1000




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


Publications:



Title

Journal

Pubmed ID

Application

1

Silencing COX-2 blocks PDK1/TRAF4-induced AKT activation to inhibit fibrogenesis during skeletal muscle atrophy.

Redox Biology

33152664

IHC

2

Single-cell RNA-Seq reveals the transcriptional landscape and heterogeneity of skin macrophages in Vsir-/- murine psoriasis.

Theranostics

32929361

IHC

3

Anti-Atherosclerosis Effect of Angong Niuhuang Pill via Regulating Th17/Treg Immune Balance and Inhibiting Chronic Inflammatory on ApoE-/- Mice Model of Early and Mid-Term Atherosclerosis.

Frontiers in Pharmacology

32082145

IHC

4

Gaudichaudione H Inhibits Inflammatory Responses in Macrophages and Dextran Sodium Sulfate-Induced Colitis in Mice.

Frontiers in Pharmacology

32009962

IHC

5

Human amnion mesenchymal stem cells attenuate atherosclerosis by modulating macrophage function to reduce immune response.

International Journal of Molecular Medicine

31364743

IHC

6

IL-17A Can Promote Propionibacterium acnes-Induced Sarcoidosis-Like Granulomatosis in Mice.

Frontiers in Immunology

31474992

IHC

7

C1q/TNF-related protein-9 promotes macrophage polarization and improves cardiac dysfunction after myocardial infarction.

Journal of Cellular Physiology

30953351

IF

8

Galectin-3 Mediates Endothelial-to-Mesenchymal Transition in Pulmonary Arterial Hypertension.

Aging and Disease

31440380

IHC

9

Carotid baroreceptor stimulation in obese rats affects white and brown adipose tissues differently in metabolic protection.

Journal of Lipid Research

31126973

IHC

10

CXCL12/CXCR4 promotes inflammation-driven colorectal cancer progression through activation of RhoA signaling by sponging miR-133a-3p.

Journal of Experimental & Clinical Cancer Research : CR

30678736

IHC/IF


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