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Anti -G-CSF Rabbit pAb

價格: 在線咨詢
貨號:
DRF101646
產品規格:
100 μL
Applications:
Species:
購買數量:
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產品詳情 操作說明 注意事項

Product Information


Description

G-CSF rabbit polyclonal

Protein full name

Granulocyte colony-stimulating factor

Synonyms

G-CSF, Csf3, Csfg, CSF3, GCSA

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse G-CSF

Isotype

IgG

Purity

Affinity purification

Predicted MW.

22 kDa

Observed MW.

19 kDa

Uniprot ID

P09920, P97712




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 800

kidney, lung, liver




Background


Granulocyte colony-stimulating factor (G-CSF), also referred to as CSF3, is a protective cytokine with anti-inflammatory effects. G-CSF is important in promoting survival of the granulocytic lineage cells and proliferation and migration of neutrophils as well as trophoblast cells. G-CSF acts by binding to its receptor G-CSFR (also called CSF3R), which after binding with G-CSF activates the canonical Janus kinase (Jak)/signal transducer, activator of transcription (STAT)and Ras/Raf/MAP kinase pathways. G-CSF potently stimulates the proliferation and release of peripheral blood progenitor cells into the bloodstream and is therefore used to treat neutropenia after chemotherapy. Furthermore, G-CSF levels are elevated upon intensive exercise leading to increased neutrophil counts, which are predominantly due to delayed neutrophil apoptosis.




Images


image.png

Western blot analysis of G-CSF (GB111039) at dilution of 1: 800

Lane 1: Mouse kidney tissue lysate

Lane 2: Mouse lung tissue lysate

Lane 3: Mouse liver tissue lysate

Lane 4: Rat kidney tissue lysate

Lane 5: Rat lung tissue lysate

Lane 6: Rat liver tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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