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Product Information
Description |
GIT2 rabbit polyclonal |
Protein full name |
ARF GTPase-activating protein GIT2 |
Synonyms |
ARF GAP GIT2, GRK-interacting protein 2, Git2, Cool-interacting tyrosine-phosphorylated protein 2, CAT-2, G protein-coupled receptor kinase-interactor 2 |
Immunogen |
Recombinant protein corresponding to Mouse GIT2 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Nucleus |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IHC |
Human, Mouse, Rat |
1: 1000-1: 4000 |
colon, breast cancer, small intestine |
IF |
Human, Mouse, Rat |
1: 500-1: 1000 |
colon, breast cancer, small intestine |
Background
This gene encodes a member of the GIT protein family. GIT proteins interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. This gene undergoes extensive alternative splicing; although ten transcript variants have been described, the full length sequence has been determined for only four variants. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding.
Images
Immunohistochemistry analysis of paraffin-embedded human colon using GIT2 (GB111092) at dilution of 1: 2000 |
|
Immunohistochemistry analysis of paraffin-embedded human breast cancer using GIT2 (GB111092) at dilution of 1: 2000 |
|
Immunohistochemistry analysis of paraffin-embedded rat small intestine using GIT2 (GB111092) at dilution of 1: 1000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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