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產品詳情
操作說明
注意事項
Product Information
|
Description |
FOXO4 rabbit polyclonal antibody |
|
Protein full name |
Forkhead box protein O4 |
|
Synonyms |
Fork head domain transcription factor AFX1, FOXO4, AFX, AFX1, MLLT7 |
|
Immunogen |
Recombinant protein corresponding to Human FOXO4 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
54 kDa |
|
Observed MW. |
54 kDa |
|
Uniprot ID |
P98177, D4A433 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Rat |
1: 500-1: 1000 |
293T, MDA-MB-231, Jurkat |
Background
FOXO4, also named as AFX, AFX1 and MLLT7, is a transcription factor which involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1.FOXO down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is involved in negative regulation of the cell cycle. A chromosomal aberration involving FOXO4 is found in acute leukemias.
Images
|
|
Western blot analysis of FOXO4 (GB111173) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區黃山路602號合肥國家大學科技園A401室