服務熱線
400-1016-218
聯系方式
- 手機：400-1016-218
- Q Q：355185756
- 郵箱：355185756@qq.com
- 地址：安徽省合肥市高新區黃山路602號合肥國家大學科技園A401室
產品詳情
操作說明
注意事項
Product Information
|
Description |
BIK rabbit polyclonal antibody |
|
Protein full name |
Inward rectifier potassium channel 2 |
|
Synonyms |
Inward rectifier K(+) channel Kir2.1, IRK-1, Potassium channel, inwardly rectifying subfamily J member 2, Kcnj2, Irk1 |
|
Immunogen |
Recombinant protein corresponding to Mouse BIK |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
48 kDa |
|
Observed MW. |
55 kDa |
|
Uniprot ID |
P35561, Q64273 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
brain |
Background
KCNJ2, also named as HHBIRK1, HHIRK1, IRK1, KIR2.1, LQT7 and SQT3, belongs to the inward rectifier-type potassium channel family. KCNJ2 probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ2 can be blocked by extracellular barium or cesium. Defects in KCNJ2 are the cause of long QT syndrome type 7 (LQT7). Defects in KCNJ2 are the cause of short QT syndrome type 3 (SQT3).
Images
|
|
Western blot analysis of KIR2.1 (GB111433) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
凡合肥萬物生物科技有限公司銷售的產品均有嚴格的質量保證。如發現產品存在包裝規格疑問，請于收貨之日起七日內向我公司總部或當地辦事處提出，并請保證該產品，以備本公司進行核對檢驗。如果發現有質量問題，請于收貨后一月內保留產品50%以上的量，以便本公司回收產品進行質檢，確認產品質量。如逾期，則視為已經對本公司產品進行驗收。 聲明：如發生產品索賠事宜，本公司僅在產品價格范圍內酌情賠償，恕不接受超出產品價格范圍之賠償?？蛻粼谑褂眠^程中有任何技術問題可以撥打技術售后服務電話我們隨時給予解答。
合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區黃山路602號合肥國家大學科技園A401室