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Anti -Nucleophosmin Rabbit pAb

價格: 在線咨詢
貨號:
KT012122
產品規格:
100 μL
Applications:
WB/IHC/IF
Species:
H/M/R,H/M/R,H/M/R
購買數量:
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產品詳情 操作說明 注意事項

Product Information



Description

Nucleophosmin rabbit polyclonal antibody

Protein full name

Nucleophosmin

Synonyms

NPM, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Numatrin, Npm1

Immunogen

Recombinant protein corresponding to Mouse Nucleophosmin

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus, Cytoplasm

Predicted MW.

33 kDa

Observed MW.

40 kDa

Uniprot ID

P06748, Q61937, P13084





Applications


Applications

Species

Dilution

Positive Sample

WB

Human, Mouse, Rat

1: 500-1: 1000

lymph node, ovary, colon

IHC/IF

Human, Mouse, Rat

1: 500-1: 3000

liver, placenta, prostate, renal cancer, testis, thymus




Background


NPM1 is a ubiquitously expressed phosphoprotein involved in ribosome assembly/transport, cytoplasmic/nuclear trafficking, regulation of DNA polymerase alpha activity, centrosome duplication, and regulation of p53. NPM1 may prevent protein aggregation via its chaperon activities, protect enzymes during thermal denaturation, and facilitate renaturation of chemically denatured proteins. The NPM1 is believed to act as the interface for oligomerization and oncogenic conversion of these tumor promoting fusion proteins.




Images


Western blot analysis of Nucleophosmin (GB111375) at dilution of 1: 500

Immunohistochemistry of paraffin embedded human liver using Nucleophosmin (GB111375) at dilution of 1: 1600 (400x lens)

Immunohistochemistry of paraffin embedded human renal cancer using Nucleophosmin (GB111375) at dilution of 1: 1600 (400x lens)


Immunohistochemistry of paraffin embedded mouse placenta using Nucleophosmin (GB111375) at dilution of 1: 1600 (400x lens)


Immunohistochemistry of paraffin embedded mouse testis using Nucleophosmin (GB111375) at dilution of 1: 1600 (400x lens)

Immunohistochemistry of paraffin embedded mouse thymus using Nucleophosmin (GB111375) at dilution of 1: 1600 (400x lens)


Immunohistochemistry of paraffin embedded rat placenta using Nucleophosmin (GB111375) at dilution of 1: 1600 (400x lens)

Immunohistochemistry of paraffin embedded rat testis using Nucleophosmin (GB111375) at dilution of 1: 1600 (400x lens)


Immunohistochemistry of paraffin embedded rat thymus using Nucleophosmin (GB111375) at dilution of 1: 1600 (400x lens)

Immunofluorescence of paraffin embedded human prostate using Nucleophosmin (GB111375) at dilution of 1: 1600 (400x lens)

Immunofluorescence of paraffin embedded mouse placenta using Nucleophosmin (GB111375) at dilution of 1: 1600 (400x lens)

Immunofluorescence of paraffin embedded mouse testis using Nucleophosmin (GB111375) at dilution of 1: 1600 (400x lens)

Immunofluorescence of paraffin embedded rat testis using Nucleophosmin (GB111375) at dilution of 1: 1600 (400x lens)



Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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